Research goals

  • Shape the bioprocess technologists of tomorrow
  • Provide generic methods for efficient and scientifically based bioprocess technologies
  • Join forces from different disciplines, such as biologists, biotechnologists, bio- process & control- engineers, and data scientists
  • Use digitalization and data science to generate, deploy and manage knowledge

Circular economy, integrated continous biomanufacturing, advanced therapies… –
Bioprocesses are the key enabler for our sustainable future and for providing affordable drugs for the world.
We are the world-leading research group innovating bioprocess technology through interdisciplinary skills and platform methods

High quality and sustainable products require stable, robust and efficient processes performing at their optimum. To achieve such optimized conditions within a process, we focus on four interconnected research topics:

  • Measurements are the basis for understanding and process control. Therefore, the development, refinement and implementation of Process Analytical Technologies is a central topic within our group.
  • Based on measured data we aim to build process models and design feedback control actions. Simulation and control in process system engineering help us to efficiently plan verification experiments, to obtain reliable event prediction and to design effective controllers.
  • The Sustainable Bioprocess Solutions team is interested in replacing and substituting chemical production routes currently relying on crude oil as raw material. In particular, we are interested in recycling complex industrial streams such as high CO2 containing streams as valuable substrate for bioproduction of everyday needed fuel and bulk chemicals towards building a circular bioeconomy.
  • Integrated Bioprocess Development designs complete processes from the gene to the refined product. Our aim is to completely understand and reveal interactions between all unit operations starting from strain generation, heading to upstream and finalizing in the downstream.

Our members

Stefan Pflügl
Stefan Pflügl PostDoc
Team lead Sustainable Bioprocess Solutions
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Vanessa Karabetian
Vanessa Karabetian Administration
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Kozma Bence
Kozma BencePostDoc
Animal Cell Culture, Process Analytical Technology
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Rémi Hocq
Rémi HocqPostDoc
Sustainable Bioprocess Solutions
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Marlies Müller
Marlies MüllerCTA
Sustainable Bioprocess Solutions
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Regina Kutscha
Regina KutschaPhD-Student
Metabolic Engineering of E. coli for acetate utilization
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Ivo van den Hurk
Ivo van den HurkPhD-Student
Development of sustainable one carbon bioprocesses
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Daniel Waldschitz
Daniel WaldschitzPhD-Student
Bacteriocin production with C. glutamicum
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Fabian Müller
Fabian MüllerPhD-Student
Soft-sensing of cell death and product formation
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Bianca Mikulasek
Bianca MikulasekPhD-Student
Transfer learning for PAT and process models
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Josef Alexander Horvath
Josef Alexander HorvathPhD-Student
Development of microbial gas fermentation processes
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Valentin von Werz
Valentin von WerzPhD-Student
Method development and characterization of NK cell cultures
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Angeliki Sitara
Angeliki SitaraPhD-Student
Sustainable Bioprocess Solutions
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Rüdiger Lück
Rüdiger LückPhD-Student
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Vinzenz Abt
Vinzenz AbtPhD-Student
ENROL – doctoral program
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Renaud Eynard
Renaud EynardPhD-Student
Sustainable Bioprocess Solutions
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Bettina Semler
Bettina SemlerProject Researcher
Sustainable Bioprocess Solutions
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Matthias Petsch
Matthias PetschCTA
Digitalization and Automation
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Uliana Smirnova
Uliana SmirnovaStaff in Research
Sustainable Bioprocess Solutions
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Niklas Pauk
Niklas PaukPhD-Student
Re-folding and modelling of re-folding kinetics
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Chika Igwe
Chika IgwePhD-Student
Re-folding analytics & intensification
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